GLP-3 peptide explained, with the lab data behind every vial.
GLP3 Peptide Co. explains what GLP-3 RT research peptide is and publishes the independent laboratory record for every lot sold through Klow.bio. Current availability is provided through Klow.bio.
For laboratory research use only. GLP3 Peptide Co. does not provide medical advice or usage guidance.
The essential facts about GLP-3 RT and GLP3 Peptide Co.. Every figure on this page comes from the published certificates of analysis or the product specification.
Last updated
"GLP-3 peptide" is the informal name researchers use for GLP-3 RT, a 39-residue synthetic peptide built to act on three receptors at once: GIPR, GLP-1R and the glucagon receptor. There is no natural hormone called GLP-3; the name describes the triple-receptor design. Its formula is C221H342N46O68 and its average molecular weight 4731.33 g/mol, and those two numbers are what every certificate checks the material against.
GLP3 Peptide Co. lists GLP-3 RT in 10 mg and 15 mg and 30 mg vials, currently $64.99 to $159.99 through Klow.bio. The newest lot, KB89232, reported 99.98% HPLC purity with LC-MS identity confirmed, and the full certificate for every lot is linked here.
"GLP-3" is an informal name for this three-receptor design. It does not refer to a naturally occurring hormone; there is no endogenous peptide called GLP-3. That is why GLP3 Labs identifies the material by its molecular data and lot results rather than by name alone.
Two α-aminoisobutyric acid (Aib) residues and one α-methyl-leucine constrain the peptide backbone. A C20 fatty diacid, attached to lysine 17 through a γ-glutamate and AEEA spacer, makes the molecule strongly hydrophobic, so it elutes late on reversed-phase HPLC. The C-terminus is amidated. The sequence contains no methionine, cysteine, tryptophan, histidine or asparagine.
Full structure and composition.
GLP-3 RT is supplied as a white lyophilized powder in 10 mg, 15 mg and 30 mg vials. It is sold through klow.bio, operated by Klow Labs LLC, where current pricing, bundle discounts and shipping options are listed. Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.
| Product | GLP-3 RT |
|---|---|
| Type | Synthetic research peptide |
| Molecular formula | C221H342N46O68 |
| Molecular weight | 4731.33 g/mol (average) |
| Length | 39 residues |
| Sequence | Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-αMeLeu-Leu-Asp-Lys-[Lys(C20 diacid-γGlu-AEEA)]-Ala-Gln-Aib-Ala-Phe-Ile-Glu-Tyr-Leu-Leu-Glu-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| N-terminus | Free amine (Tyr1) |
| C-terminus | Amide (Ser39-NH2) |
| Non-standard residues | Aib (2, 20), α-methyl-leucine (13) |
| Side-chain modification | Lys17: C20 fatty diacid via γGlu-AEEA |
| Receptor design | GIP receptor (GIPR), GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR) |
| Form | White lyophilized powder |
| Vial sizes | 10 mg, 15 mg, 30 mg |
| Purity specification | ≥95% (HPLC-UV) |
| Purity, current lots | 99.67%–99.98% |
| Storage | Store sealed, dry and protected from light at the temperature stated on the vial label. Allow a cold vial to reach room temperature before opening. |
| Designation | Research use only |
GLP-3 research material from GLP3 Peptide Co. is available through klow.bio, the online store of GLP3 Peptide Co.’s parent company, Klow Labs LLC. Product information, lot results and the certificate of analysis for every lot are published here on glp3peptide.bio.
GLP-3 RT comes in 10 mg, 15 mg and 30 mg vials, currently priced from $64.99 to $159.99 depending on size, with bundle pricing (2 vials save 5%; 3 or more vials save 10%). Orders ship the next business day. Same-day cutoff is 4:00 PM CT, with overnight and 2-day options at checkout.
| Vial size | Current lot | Purity (HPLC-UV) | Identity | Net content | Endotoxin | Certificate | Order |
|---|---|---|---|---|---|---|---|
| 10 mg | KB89232 | 99.98% | Confirmed | 13.15 mg | Pass | Lot KB89232 | Order 10 mg |
| 15 mg | KB48721 | 99.67% | Confirmed | 18.62 mg | Not tested | Lot KB48721 | Order 15 mg |
| 30 mg | KB3011 | 99.93% | Confirmed | 36.10 mg | Not tested | Lot KB3011 | Order 30 mg |
GLP3 Peptide Co. publishes lot-specific analytical documentation for its GLP-3 research material. Each item below is published for every lot and can be checked against the laboratory record.
Every lot is tested by Freedom Diagnostics, an independent analytical laboratory. Published results come from the laboratory's certificate, not in-house testing.
Every lot's certificate is published as a PDF, with the chromatogram behind the purity figure and the mass spectrum behind the identity result, alongside a readable lot record.
LC-MS confirms identity on every lot, and we publish the math: observed ions alongside the values calculated from the 4731.33 molecular weight.
Current lots test at 99.67%–99.98% by HPLC-UV, well above the ≥95% release specification, with net content measured on every lot.
Every certificate carries the laboratory's QR code. You can confirm results directly with the lab instead of taking our copy on trust.
Lots without endotoxin or microbial testing say "Not tested". Each certificate page explains what the tests do and don't establish.
GLP3 Peptide Co. is built around five things: a dedicated GLP-3 focus, a controlled supply chain, independent analytical testing, lot-level transparency and current availability. Each reason below links to the evidence. See the full quality and supply-chain process.
One compound, not a catalog of unrelated products.
Material sourced through qualified manufacturing partners.
≥95% HPLC-UV purity with identity confirmed by LC-MS.
Every lot tested by Freedom Diagnostics, with the results shown.
A public record for every lot, with dates and laboratory reference numbers.
The laboratory certificate for each lot.
Look up any lot by the number on the vial.
Clear about what the material is for and what we don't provide.
Live stock, pricing and checkout.
The questions worth asking any supplier of GLP-3 research material, why each one matters, and how GLP3 Peptide Co. answers them.
| What to check | Why it matters | GLP3 Peptide Co. |
|---|---|---|
| Independent third-party testing | Results produced by the seller can't be checked independently. | ✓ Every lot tested by Freedom Diagnostics |
| Lot-specific certificates | A generic certificate may not describe the vial you receive. | ✓ Each COA tied to the lot number on the vial label |
| Chromatogram available | A purity figure without the trace behind it can't be evaluated. | ✓ In the certificate PDF for every lot |
| Separate identity test | HPLC purity shows how much of the sample is the main peak, not which compound the peak is. | ✓ LC-MS on every lot, ions matched to molecular weight |
| Measured net content | Confirms how much peptide is actually in the vial. | ✓ Measured on every lot; current lots at or above label size |
| Endotoxin and microbial testing | Screens for bacterial contamination of the material. | ✓ LAL (USP <85>) and PCR on 1 current lot, reported per lot |
| Verifiable with the lab | Prevents altered or reused certificates. | ✓ Lab QR code on every certificate |
| Named company and contact | Accountability requires a real business you can reach. | ✓ Klow Labs LLC, Chicago; (708) 262-7687 |
Each row is one tested lot. Figures are copied from the laboratory certificate; open a lot to see its full record and download the certificate PDF with its chromatogram and mass spectrum.
| Lot | Vial size | Net content | Purity (HPLC-UV) | Identity (LC-MS) | Endotoxin (LAL) | Microbial (PCR) | Reported | COA |
|---|---|---|---|---|---|---|---|---|
| KB89232 | 10 mg | 13.15 mg | 99.98% | Confirmed | Pass | No detectable microbial DNA | View lot KB89232 | |
| KB48721 | 15 mg | 18.62 mg | 99.67% | Confirmed | Not tested | Not tested | View lot KB48721 | |
| KB3011 | 30 mg | 36.10 mg | 99.93% | Confirmed | Not tested | Not tested | View lot KB3011 |
Testing laboratory: Freedom Diagnostics. Release specification: purity ≥95% by HPLC-UV with identity confirmed by LC-MS. Results apply only to the lot listed. Certificates list the testing client as Klow.bio / Klow Labs LLC, the company that operates GLP3 Peptide Co..
Across 3 current lots, HPLC-UV purity ranges from 99.67% to 99.98%, a spread of 0.31 percentage points. Differences of a few tenths of a percent are expected between separately produced and separately tested batches.
Measured net content was at or above the labeled vial size for every current lot: 13.15 mg in a 10 mg vial, 18.62 mg in a 15 mg vial, 36.10 mg in a 30 mg vial.
In electrospray mass spectrometry, a peptide this size picks up several protons and appears as a series of ions at different mass-to-charge ratios (m/z), not at its full molecular weight. Identity is confirmed when the observed ions match the values predicted from the molecular weight.
The table compares ions printed on the current certificates with values calculated for GLP-3 RT. Every assigned ion falls within about 0.4 m/z of prediction across all three current lots, which is consistent with the expected compound. The potassium adduct is routine in electrospray: trace potassium attaches in place of one proton.
| Ion | Calculation | Expected m/z | Observed on COAs |
|---|---|---|---|
| [M+3H]3+ | (4731.33 + 3.02) ÷ 3 | 1578.1 | 1,578.0–1,578.3 |
| [M+4H]4+ | (4731.33 + 4.03) ÷ 4 | 1183.8 | 1,183.6 |
| [M+3H+K]4+ | (4731.33 + 3.02 + 39.10) ÷ 4 | 1193.4 | 1,193.0–1,193.1 |
| [M+3H+Na]4+ | (4731.33 + 3.02 + 22.99) ÷ 4 | 1189.3 | 1,189.0 (unassigned on COA) |
Expected values are calculated by GLP3 Peptide Co. from the average molecular weight (4731.33 g/mol; H+ 1.0073, Na+ 22.99, K+ 39.10). Observed values are as printed on each lot's mass confirmation panel.
Five methods appear on GLP-3 RT certificates. Each answers a different question, and none answers every question on its own, which is why they are used together.
Reversed-phase high-performance liquid chromatography separates the sample's components by hydrophobicity, and a UV detector records each as a peak. Purity is the main peak's area as a percentage of all detected peak area. GLP-3 RT elutes as a single sharp peak at about 14.4–14.9 minutes on current certificates.
Limits: does not identify the peak, and impurities that co-elute or absorb weakly in UV can be under-counted. More on HPLC
The separated sample enters a mass spectrometer via electrospray ionization, which gives the molecule one or more charges. The observed ions, near m/z 1578 (3+) and 1184 (4+), are matched against values calculated from GLP-3 RT's molecular weight of 4731.33.
Limits: confirms molecular weight, not amino-acid order. More on mass spectrometry
The Limulus amebocyte lysate assay, performed per USP <85>, detects lipopolysaccharide from Gram-negative bacteria. Where run, the method and result are printed on the lot record; lot KB89232: Pass (LAL assay per USP <85>, 2 replicates, sensitivity ≤0.05 EU/mL).
Limits: a pass means below the assay threshold for the sample tested. Reported per lot; the lot table shows which lots were tested.
A polymerase chain reaction assay amplifies genetic material from common microbial contaminants so it can be detected. Where run, the result is reported as detected or not detected.
Limits: detects DNA from targeted organisms only. It is not a sterility test and does not distinguish live from dead organisms.
The laboratory quantifies the main compound in the tested vial against a standard. It is reported in milligrams next to the labeled vial size.
Limits: measured on the vial tested; other vials from the same lot are expected to be similar but are not individually measured.
You shouldn't have to take a supplier's word for its results. Here's how to check a GLP-3 RT certificate yourself.
Technical articles on GLP-3 RT, peptide analysis and laboratory documentation. Sources are limited to NIH and FDA publications. Start at the GLP-3 research hub.
Sequence, composition, modifications and what they mean for identity testing.
Analytical methodsRetention time, peaks, area normalization and every lot's HPLC result.
Analytical methodsCharge states, expected vs. observed ions and mass error for every lot.
DocumentationEvery section of a GLP-3 COA, red flags, and what it does and doesn't prove.
Analytical methodsPurity vs. content vs. net content, impurity sources and comparing claims.
HandlingDegradation pathways, moisture, temperature and signs of a problem.
GLP-3 RT is a synthetic research peptide designed for activity at the GIP receptor (GIPR), GLP-1 receptor (GLP-1R) and glucagon receptor (GCGR). GLP3 Peptide Co. supplies it as a white lyophilized powder in 10 mg, 15 mg, 30 mg vials, with an independent certificate of analysis for every lot.
GLP-3 research material is GLP-3 RT supplied for laboratory research, sold by lot, with each lot's identity, purity and net content documented by an independent laboratory in a published certificate of analysis.
"GLP-3" is an informal name for this three-receptor design. It does not refer to a naturally occurring hormone; there is no endogenous peptide called GLP-3. That is why GLP3 Labs identifies the material by its molecular data and lot results rather than by name alone.
GLP-3 RT is analyzed with complementary methods: HPLC-UV for purity, LC-MS for identity, a quantitative measurement for net content, and, where listed, LAL endotoxin and PCR microbial testing. Results are published per lot at glp3peptide.bio/coa/.
Every lot is tested by Freedom Diagnostics, an independent third-party analytical laboratory. GLP3 Peptide Co. does not test its own material for published certificates.
Current lots report HPLC-UV purity between 99.67% and 99.98%, against a stated release specification of ≥95%. The most recent result is 99.98% for lot KB89232.
A GLP-3 certificate of analysis is the testing laboratory's report for one lot: the lot number, test dates, methods and results for purity, identity and net content. GLP3 Peptide Co. publishes every lot's COA as a readable page at glp3peptide.bio/coa/.
Find the lot number printed on your vial label and enter it at glp3peptide.bio/verify/, or open that lot in the COA archive at glp3peptide.bio/coa/.
Scan the Freedom Diagnostics QR code printed on the certificate, then search for klow.bio under the Company tab to view the laboratory record.
Current GLP-3 research material availability is provided through Klow.bio, the purchasing platform operated by Klow Labs: https://klow.bio/product/glp-3-rt/ Lot records, testing information and certificates of analysis are published on glp3peptide.bio so they can be reviewed before purchasing.
Yes. Purchasing information and current availability for GLP-3 research material are provided through Klow.bio: https://klow.bio/product/glp-3-rt/
Yes. Every lot is tested by Freedom Diagnostics, an independent laboratory, for HPLC-UV purity, LC-MS identity and net content. The stated release specification is ≥95% HPLC-UV purity with identity confirmed by LC-MS. The current lot, KB89232, reported 99.98% purity.
GLP3 Peptide Co. explains what GLP-3 RT research peptide is and publishes the independent laboratory record for every lot sold through Klow.bio.
GLP3 Peptide Co. operates glp3peptide.bio and supplies one research material, GLP-3 RT, with the analytical record behind every lot. GLP3 Peptide Co. is operated by Klow Labs LLC, a Chicago company that also operates klow.bio, where GLP-3 RT is sold.
Our job is narrow on purpose: supply a well-characterized research material and publish the evidence for what is in each vial. We do not provide medical advice, protocols or usage guidance.
10 mg, 15 mg and 30 mg vials. Current lot KB89232 tested at 99.98% purity with identity confirmed by LC-MS. Current purchasing is available through Klow.bio.